About Us

DELFI Diagnostics, Inc. (DELFI Diagnostics) is developing next-generation, blood-based tests that are reliable, accessible and deliver a new way to help detect cancer. Employing advanced machine-learning methods to whole-genome sequencing data, the DELFI ("DNA EvaLuation of Fragments for early Interception") platform is built to address the highest-burden health challenges. DELFI Diagnostics prioritizes solutions that have the potential to save lives on a global scale, including for historically underserved populations. DELFI Diagnostics’ platform relies on fragmentomics – the discovery that cancer cells are more chaotic than normal cells and, when they die, leave behind tell-tale patterns and characteristics of cell-free DNA (cfDNA) fragments. FirstLook Lung, for individuals eligible for lung cancer screening, is DELFI Diagnostics’ first laboratory-developed screening test and can be part of routine blood work. FirstLook Lung uses millions of data points to reliably identify individuals who may have cancer detected through low-dose CT, including early stage disease with a negative predictive value of 99.8 percent. This test has not been cleared or approved by the FDA.

What You'll Do

• Manage and lead a team of software and bioinformatics engineers, software & data architect, and software product managers
• Oversee the productization and delivery of cutting-edge machine learning algorithms to detect cancer from blood samples
• Partner as needed with regulatory and software QA/testing/cybersecurity teams to maintain software as a medical device underlying diagnostic product(s) on market
• Collaborate with peers leading assay design & development, laboratory operations, data science, and clinical development to substantively advance DELFI's R&D objectives
• Develop and continuously improve software solutions for EHR integration and LIMS to enable machine learning as well as commercial sales
• Partner with IT & cybersecurity team lead to develop a 2-3 year technology roadmap, including in-house tooling for GenAI and ML infrastructure
• Represent DELFI externally with collaborators and vendors

What You'll Bring to DELFI

Required

• Degree in any of the quantitative sciences (Applied Math, Physics, Chemistry, Computer Science) or Engineering
• 10+ years of software leadership experience in industry including track record of successfully developing and deploying lab and enterprise software, scalable data systems, and/or production ML infrastructure
• 15+ years expertise in programming including production compute environments (AWS/Nvidia), data systems (Postgres, RDS), and versioning principles for reproducible model-building and evaluation
• 10+ years of experience leading and managing teams exemplifying best practice in recruiting, team-building, employee performance management and career development, goal-setting, and cross-functional collaboration
• Superb written, verbal communication, and influencing and presentation skills, including the ability to communicate complex concepts succinctly to a variety of audiences
• Decisive, intellectually curious, proactive, and composed with a balance of high IQ and EQ

Preferred

• 5+ years of experience working in biotech/pharma/diagnostics
• Background or interest in cancer genomics, molecular biology, and the latest genotyping and phenotyping techniques